Spravato Treatment

Spravato (esketamine) is a relatively new way to manage Treatment-Resistant Depression (TRD). Taken in conjunction with an oral anti-depressant, this nasal spray is fast acting, with studies showing improvement as soon as a few hours after ingestion. Traditional antidepressants usually take a few weeks for results to appear. If you have tried two or more depression treatments with little to no success, Spravato may be the right choice to help you get your life back on track.  Please call our office to schedule your consultation.

SPRAVATO® (esketamine) CIII Nasal Spray is indicated, in conjunction with an oral antidepressant, for the treatment of:

• Treatment-resistant depression (TRD) in adults.
• Depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation or behavior.

Symptoms associated with major depressive disorder may include:

  • Depressed mood or feelings of sadness
  • Disrupted sleep
  • Lack of interest or inability to feel pleasure (anhedonia)
  • Feelings of guilt or hopelessness
  • Lack of energy
  • Difficulty concentrating
  • Changes in appetite or weight
  • Slowed thoughts or movements (psychomotor retardation)
  • Restlessness and/or purposeless movements (psychomotor agitation)
  • Suicidal thoughts or actions

How will I take SPRAVATO®?

  • You will take SPRAVATO® nasal spray yourself, under the supervision of a healthcare provider in a healthcare setting. Your healthcare provider will show you how to use the SPRAVATO® nasal spray device.
  • Your healthcare provider will tell you how much SPRAVATO® you will take and when you will take it.
  • Follow your SPRAVATO® treatment schedule exactly as your healthcare provider tells you to.
  • During and after each use of the SPRAVATO® nasal spray device, you will be checked by a healthcare provider who will decide when you are ready to leave the healthcare setting.
  • You will need to plan for a caregiver or family member to drive you home after taking SPRAVATO®.
  • If you miss a SPRAVATO® treatment, your healthcare provider may change your dose and treatment schedule.
  • Some people taking SPRAVATO® get nausea and vomiting. You should not eat for at least 2 hours before taking SPRAVATO® and not drink liquids at least 30 minutes before taking SPRAVATO®.
  • If you take a nasal corticosteroid or nasal decongestant medicine, take these medicines at least 1 hour before taking SPRAVATO®.